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This occurs in deficiencies of vitamin B12 or folic acid (macrocytic hyperchromic anemia). 2.Hemoglobin synthesis is impaired. This situation arises in iron deficiency, since Fe2+ is a constituent of hemoglobin (microcytic hypochromic anemia). Vitamin B12 (B) Vitamin B12 (cyanocobalamin) is produced by bacteria; B12 generated in the colon, however, is unavailable for absorption (see below).
Combination therapy prevents the emergence of resistant mycobacteria. Because the antibacterial effects of the individual substances are additive, correspondingly smaller doses are sufficient. Therefore, the risk of individual adverse effects is lowered. Most drugs are active against only one of the two diseases.

 

Interferons are also used to treat certain malignancies and autoimmune disorders (e. g. , IFN-? for chronic hepatitis C and hairy cell leukemia; IFN-? for severe herpes virus infections and multiple sclerosis). Virustatic antimetabolites are “false” DNA building blocks (B) or nucleosides. A nucleoside (e. g. , thymidine) consists of a nucleobase (e. g. , thymine) and the sugar deoxyribose.
Included among these are “transmitters” released from nerves, which the cell is able to recognize with the help of specialized membrane binding sites or receptors. Hormones secreted by endocrine glands into the blood, then into the extracellular fluid, represent another class of chemical signals.

 

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